Schizophrenia with Dr. Cummings: Controversies, Brain Science, Crime, History, Exercise, Successful Treatment

In this episode, Dr. Puder addresses the fascinating realm of schizophrenia with Dr. Cummings, a previous guest in the show. Dr. Cummings is a psychiatrist with a wealth of experience from working at Patton State Hospital in California, one of the biggest forensic hospitals in the world.

  • Defining Schizophrenia
    • Swedish survey about misperceptions of the environment found that roughly 50% of the population have had misperceptions that could be considered psychotic in nature.
  • The Loss of Brain in Schizophrenia
    • Schizophrenic patients lose 2% of brain mass per year for the first 5 year in the course of illness.
  • Living with Schizophrenia and Perception of Reality
  • Are Negative Symptoms in Schizophrenia Precipitated by Medications?
  • The Pathology, Biology, and Genetics of Schizophrenia
  • Cannabis Use and Risk For Schizophrenia
  • Counter-arguments Against Robert Whitaker’s “Anatomy of an Epidemic”    
    • Emil Kraepelin, and the Early Studies on Schizophrenia
      • The majority of schizophrenic patients during Kraepelin’s observation became vegetative in their 40s.
      • After the advent of antipsychotic medications, schizophrenic patients are able to function until their 70s-80s
    • Gitlin 2001 Neuroleptic Discontinuation Study
      • Exacerbation or relapse was almost universal within 2 years in those who discontinued antipsychotics
  • Schizophrenia Prevention in High Risk Population
    • Australian study on children of schizophrenic parents (Yung, 2011)
  • Australian Study on Children of Schizophrenic Parents
  • Crime, Violence, Mass Shootings and Schizophrenia
  • Medical Management of Schizophrenia
  • 1st Break Psychosis
  • Long-acting Injectable Antipsychotics in Early Illness
  • Medication Adherence
  • Exercise
    • Exercise for schizophrenia increased hippocampal size by 12% vs. -1% for non exercising groups of patients (Pajonk, 2010)
  • Lifestyle, Diet Optimization
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